- What is trazodone used to treat?
- How is trazodone metabolized and excreted?
- What are the side effects of trazodone discontinuation?
- Is trazodone hydrochloride safe to take with other medications?
- What does trazodone do to the brain?
- What is trazodone used for off label?
- Can you take Trazodone for sleep?
- Is trazodone approved for use in children?
- How is trazodone metabolized in the liver?
- How long does trazodone stay in your system?
- Does ketoconazole inhibit trazodone metabolism?
- How is tramadol excreted from the body?
- Does trazodone cause withdrawal symptoms?
- How do I know when to taper off trazodone?
- How effective is trazodone compared to other medications?
- What are the possible side effects of trazodone (dextroamphetamine)?
- What should I know about trazodone before taking it?
- Is trazodone hydrochloride the same as acetaminophen?
- What are the effects of mixing alcohol and trazodone?
- What are the ingredients in trazodone hydrochloride?
What is trazodone used to treat?
Trazodone is used to treat depression. It is thought to work by increasing the activity of serotonin in the brain. Trazodone is an antidepressant. This medicine is available only with your doctors prescription. Copyright © 2021 IBM Watson Health. All rights reserved.
How is trazodone metabolized and excreted?
Trazodone is extensively metabolized; less than 1% of an oral dose is excreted unchanged in the urine. In some patients Trazodone may accumulate in the plasma. Trazodone is 89 to 95% protein bound in vitro at concentrations attained with therapeutic doses in humans.
What are the side effects of trazodone discontinuation?
Trazodone may cause a discontinuation syndrome if abruptly stopped, symptoms include anxiety, agitation, and sleep disturbances. When the time comes to withdraw trazodone, the dosage should be tapered off slowly under a doctors advice.
Is trazodone hydrochloride safe to take with other medications?
If concomitant use of Trazodone with other serotonergic drugs is clinically warranted, inform patients of the increased risk for serotonin syndrome and monitor for symptoms. Clinical studies indicate that Trazodone hydrochloride may be arrhythmogenic in patients with preexisting cardiac disease.
What does trazodone do to the brain?
Trazodone is an antidepressant medicine. It affects chemicals in the brain that may be unbalanced in people with depression. Trazodone is used to treat major depressive disorder. It may help to improve your mood, appetite, and energy level as well as decrease anxiety and insomnia related to depression.
What is trazodone used for off label?
Trazodone is also used off-label for anxiety, Alzheimer disease, substance abuse, bulimia, and fibromyalgia due to its serotonergic receptor antagonism and serotonin reuptake inhibiting effects. Trazodone has also been used for post-traumatic stress disorder (PTSD) if the first-line treatment use of SSRIs does not show efficacy.
Can you take Trazodone for sleep?
Read on to learn about the risks and benefits of taking trazodone for sleep. Trazodone has been approved by the U.S. Food and Drug Administration for treating depression, but doctors often prescribe it for insomnia. The drug has sedative effects, which is why it is sometimes used for sleep problems.
Is trazodone approved for use in children?
Trazodone is not approved for use in pediatric patients. Is it approved for use as a sleep aid? Though the FDA has approved trazodone for use as a treatment for depression in adults, for many years doctors have also prescribed it as a sleep aid. The FDA approves medications to treat specific conditions based on clinical trials.
The half-life of trazodone is 3-6 hours in the first phase and then 5-9 hours in the second phase. This is the process of how the drug leaves the body, or excretion. Trazodone is excreted mainly in the urine. So how exactly does trazodone work?
Does ketoconazole inhibit trazodone metabolism?
Does trazodone cause withdrawal symptoms?
It appears that taking a drug like trazodone for a longer period of time or in higher doses will increase the length and severity of the withdrawal symptoms. Withdrawal from trazodone conforms to the withdrawal pattern from other antidepressants that primarily affect the neurotransmitter serotonin.
How do I know when to taper off trazodone?
The taper can be slowed down or sped up depending on your needs. If you are beginning to feel the onset of withdrawal symptoms, this may be a sign that the taper is occurring too rapidly and should be dialed back. Slow and steady is the goal of a trazodone taper.
How effective is trazodone compared to other medications?
Data collected from double-blind studies indicate that the effectiveness of Trazodone is similar to that of other drugs including: Amitriptyline, Doxepin, and Mianserin.
What are the possible side effects of trazodone (dextroamphetamine)?
Applies to trazodone: compounding powder, oral tablet, oral tablet extended release The most commonly reported side effects included drowsiness, dry mouth, dizziness, and lightheadedness. [ Ref] Very common (10% or more): Drowsiness (up to 41%), dizziness (up to 28%), lightheadedness (up to 28%), headache (up to 20%)