What is adapalene?

Adapalene is a research product of Galderma Laboratories, France. Adapalene was approved in 1996 by the U.S. Food and Drug Administration (FDA) for use in the treatment of acne. In the United States, adapalene is available under the brand name Differin in three preparations: 0.1% cream, 0.1% gel, and 0.3% gel.

How effective is adapalene for acne?

Adapalene is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne, and is also used off-label to treat keratosis pilaris as well as other skin conditions. Among topical retinoids used to treat acne vulgaris, adapalene is considered to be the least effective, but best tolerated.

What are the instructions for using adapalene?

Follow all instructions closely. Do not take adapalene by mouth. Use on your skin only. If you get adapalene in any of these areas, rinse well with water. Do not put on cuts, scrapes, eczema, or damaged skin. Do not put on sunburned skin. Wash your hands before and after use. Clean affected part before use. Make sure to dry well.

Is adapalene gel better than other retinoids?

Studies have shown that compared to other retinoid, Adapalene gel 0.1% causes less irritation to the skin. Adapalene gel is oil-free, fragrance-free and dermatologist developed. Domestic Shipping: Item can be shipped within U.S.

What is the classification of adapalene?

Adapalene. Adapalene is a Retinoid. The chemical classification of adapalene is Retinoids. Adapalene is a topical retinoid-like compound, chemically similar to vitamin A. Although the exact mechanism of action is unknown, adapalene binds to specific retinoic acid receptors in the nucleus, leading to specific gene expression.

How does adapalene work for acne?

Adapalene treats acne deep in the pores at the source, prevents new acne from forming and, as a result of reduced acne, restores your skin’s natural texture and tone. Adapalene has been prescribed to more than 40 million people over the last 20 years.

What is the difference between Differin and adapalene?

In clinical studies, adapalene has shown superior tolerability to other topical prescription retinoids, meaning Differin is gentler on your skin, while still effective. Adapalene remains high in concentration, deep in the pores, to help clear and prevent acne

How do you use adapalene solution?

The solution comes in a glass bottle with an applicator and as individual pledgets (medicated wipes for one time use). Nonprescription (over the counter) adapalene comes as a gel to apply to the skin. Adapalene is usually applied once a day at bedtime.

What should I know about adapalene before using it?

Do not apply adapalene to skin that is sunburned, broken, or covered with eczema (a skin disease). If you have any of these conditions, do not apply adapalene until your skin has healed. Be careful not to get adapalene in your eyes, nose, or mouth. If you do get adapalene in your eyes, wash them with plenty of water and call your doctor.

What is the best way to apply adapalene gel?

Dr. King recommends applying a thin layer of the gel (about a pea-sized amount) onto clean, dry skin. Because adapalene works to both treat and prevent acne, it should be applied across the entire face, not as a spot treatment. As far as timing is concerned, adapalene, just like any other retinol, should be applied in the evening.

What should I avoid using adapalene gel?

Patient Counseling Information. You should avoid applying Adapalene Gel, 0.3% to cuts, abrasions and sunburned skin. You should avoid skin products that may dry or irritate your skin such as harsh soaps, astringents, cosmetics that have strong skin drying effects and products containing high levels of alcohol.

What are the side effects of adapalene gel?

The most common side effects of Adapalene Gel, 0.3% are: 1 skin pain 2 skin peeling 3 sunburn

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